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AKI is defined as an abrupt reduction in renal function within a few days or weeks [5], while CKD is defined by the presence of kidney damage or decreased kidney function for three or more months [6]

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Lentiviral-based transfection into HaCaT cells For suppression of NRF2 in HaCaT cells, lentiviral particles expressing shRNAs against human NRF2 were used to downregulate NRF2 mRNA

However, whether alterations in H 2 S production contribute to DCM has yet to be investigated