The class of medications called glucagon-like peptide-1 receptor agonists (GLP-1RAs) was first authorized in the early 2000s and includes semaglutide, which gained Food and Drug Administration (FDA) approval in 2017 for patients with Type 2 diabetes
Per the KFF 2025 Employer Health Benefits Survey, 43% of firms with 5,000-plus employees cover GLP-1s for weight loss (up from 28%), 30% of firms with 1,000 to 4,999, and 16% of firms with 200 to 999
For someone who is already feeling disconnected from their body or struggling with how it looks, using a medication that reduces hunger cues can create a slippery slope to intentional restriction, guilt, and shame around eating
Common Denials Rejections are frequently related to absent or fragile papers or from the insurer classifying the treatment as beautifying
The role of oxyntomodulin and peptide tyrosine-tyrosine (PYY) in appetite control