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First, the vast majority of available data derives from animal studies, and extrapolation to human applications may not be straightforward due to species differences in physiology and drug metabolism

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Therefore, in the absence of claims data, we proposed to continue to use our equitable adjustment authority under section 1833(t)(2)(E) of the Act to maintain the CY 2025 payment rate of $4.69 per mm 2 for HCPCS code C2645, which we proposed to be assigned to APC 2648 (Brachytx planar, p-103), for CY 2026

When -cells fail: lessons from dedifferentiation