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Beyond the observed increase in female lifespan, we show that pharmacologic blockade of IGF-1R signaling preserves, to various degrees, many aspects of healthspan, including neuromuscular function and endurance, and attenuates the age-related increase in diastolic dysfunction, systemic inflammation, and neoplasias in females

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doi: 10.1016/J.JTHA.2022.10.013 28 PretoriusEVlokMVenterCBezuidenhoutJALaubscherGJSteenkampJet al

Taylor & Francis, Washington, DC, pp 91115 Cooper AJ, Kristal BS (1997) Multiple roles of glutathione in the central nervous system

Both medications can affect the digestive system, though in different ways