In this review, we will discuss factors that have been, or actually are, associated with the development of liver injury following paracetamol exposure
Folic acid, which is the form found in fortified foods and supplements is also a poor substrate for folylpolyglutamate synthase accounting for its efficient uptake from the intestines and release to the blood
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Defects in complex I are among the most common causes of mitochondrial diseases, contributing to disorders such as Leigh syndrome, mitochondrial encephalomyopathy and Parkinsons disease by disrupting ATP production and elevating oxidative stress 21,71,72,73
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