Constant, non-pulsatile GH rise (as occurs with synthetic GH use) can lead to receptor desensitization, where target tissues become less responsive to growth hormone over time
The translational imperative for multimodal strategies becomes particularly evident in complex clinical contexts such as traumatic brain injury, where the cascade of secondary insults, excitotoxicity, inflammation, oxidative stress, and delayed neurodegeneration demands comprehensive and patient-specific interventions
Data are representative of minimum three independent experiments and the number of biological replicates is quoted in the figure legends
As with any prescription medication, the dose prescribed is for you and you alone
PubMed , Journal of Medical Toxicology , vol