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MDSCs are broadly classified in two sub-populations, the monocytic MDSC (M-MDSC) and granulocytic MDSC (G-MDSC), which exist both in humans and mice [244] [245]

To confirm whether recombinant proteins of AsGGT1, AsGGT2, and AsGGT3 were expressed as mature GGT enzymes in yeast cells, we first examined deglutamylation activities of these recombinant proteins by using the standard procedure that utilizes -glutamyl- p -nitroanilide, a common synthetic -glutamyl donor substrate for known GGTs (Orlowski and Meister, 1963)

C., Melder, R

The foundational U-shaped dose-response relationship was also documented in this original research programme