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Conversely, the use of G15 may exacerbate inflammatory responses in the tumor microenvironment, leading to the increased proliferation and migration of tumor cells [235]

Among them, four lacked three-dimensional structural information, and five exhibited ligand transfer errors (including Methotrexate predicted to target KIR2DS4), rendering them unsuitable for docking

11 The anatomical linchpin is the area postrema, a small hindbrain structure that sits outside the bloodbrain barrier and is therefore directly exposed to circulating hormones