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Weight Loss Support With the Skinny B12 Shot A skinny B12 shot often includes B12 plus additional lipotropic agents such as MIC (methionine, inositol, and choline) which help the liver metabolize fat more efficiently

However, the further clinical development of pramlintide/metreleptin combination therapy has been discontinued by the manufacturing companies because of safety concerns [249](Table 3 )

[1] [2] Blood levels of B12 may rise quickly following injection, though elevated blood levels do not immediately translate to symptom resolution

They contain medications designed to help reduce appetite and promote weight loss

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