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For example, Humira (adalimumab), an antibody vs tumor necrosis factor used as treatment for many autoimmune diseases, has a list price of over $7,000 a month and was for a decade until 2022 the leading drug by sales worldwide (peak $22 billion of sales in 2021, before patent expirations)

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Green synthesis of CaO nanoparticles improves their compatibility with human cells and incorporates phytochemicals that provide additional anticancer effects, thereby addressing challenges associated with standardization, stability, and toxicity