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Addition of GLP-1 RAs or the dual GIP and GLP-1 RA to metformin usually results in 1% to 2% lowering of A1C (105,117,118) ( Fig

Gastrointestinal reactions are often reported during dose escalation because the digestive system is adjusting to a stronger effect from the medication

And where its most relevant to our discussion is how the presence of these mutations impacts how well your body can or cant use certain formulations of B12

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