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In this Review, we summarize current preclinical and clinical evidence, showing that the riskbenefit profile of GLP1RAs remains favourable in individuals with T2DM and obesity, although caution is warranted in those with a low cardiometabolic risk, for whom the potential risks of cancer might outweigh any expected benefits

The phase 2 obesity trial for retatrutide enrolled a separate subgroup of people with obesity and NAFLD

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Ro is an established telehealth company that connects patients with licensed clinicians and prescription fulfillment