Small-fiber neuropathy (SFN): Affects pain and temperature fibers (A and C fibers)
Cardiovascular protection represents another area of investigation
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It currently makes three drugs that contain semaglutide, including: Wegovy, a once-weekly injectable medicine for weight loss and cardiovascular risk reduction Ozempic, a once-weekly injectable medicine for Type 2 diabetes and cardiovascular risk reduction, often prescribed off-label (for a non-FDA-approved use) for weight loss Rybelsus, a daily oral medicine for managing blood sugar levels in people with Type 2 diabetes, and sometimes prescribed off-label for weight loss These three brand-name medicines are the only FDA-approved semaglutide products
Updated July 24, 2026 at 5:32 PM EDT For the latest stories on the science of healthy living, subscribe to NPR's Health newsletter