As estrogen levels decrease, insulin signaling can become less efficient, meaning the pancreas may need to release more insulin to manage the same amount of glucose
Contact your GP or NHS 111 if headaches persist beyond initial weeks, worsen over time, or require increasing analgesia

Mounjaro might suit you if: Weight loss is a primary goal Mounjaro produces substantially greater weight loss in clinical trials and is licensed for weight management You want stronger blood sugar control the dual function of the drug delivers greater HbA1c reductions than GLP-1-only medications You prefer a weekly routine one injection per week with no dietary timing restrictions You want more dose flexibility six dose levels allow finer adjustments Rybelsus might suit you if: You have a strong aversion to injections Rybelsus is the only oral GLP-1 option in the UK You have type 2 diabetes and want oral treatment its an effective addition to oral diabetes management Storage convenience matters no refrigeration required at any point Cost is a factor Rybelsus is typically less expensive on private prescription Frequently asked questions Is Mounjaro more effective than Rybelsus

It is a once-weekly injectable medication that combines the effects of two naturally occurring hormones, GLP-1 (glucagon-like peptide-1) and GIP (gastric inhibitory peptide), to help regulate blood sugar levels and support weight loss
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