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Skeletal demineralization and growth retardation in inflammatory bowel disease
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It is classified as a triple receptor agonist for its capacity to simultaneously engage the glucose-dependent insulinotropic polypeptide (GIP) receptor, glucagon-like peptide-1 (GLP-1) receptor, and glucagon receptor a receptor profile that differentiates it from the single- and dual-receptor agonists more commonly evaluated in metabolic pharmacology research
The treatment also decreased pro-inflammatory and pro-fibrotic gene expression with reduced macrophage infiltration (Li et al., 2025)
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