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50 years ago in The Journal of Pediatrics: The use of N-acetylcysteine in the treatment of cystic fibrosis

These liposomes are composed of phospholipidsthe same materials that make up cell membranescreating a protective barrier that shields glutathione from degradation while facilitating cellular uptake

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EDC/NHS chemistry was used to graft functional groups (alanine and GSH), couple therapeutic molecules (ibuprofen and dopamine) on PLG backbone and label the co-polypeptides with R6G (Fig