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Diabetes patients using Ozempic were found to be over twice as likely to develop a rare eye condition known as NAION compared to those taking other diabetes medications, according to researchers who analyzed years of patient data from Denmark and Norway.

However, tolerability, discontinuation rates, and comparative efficacy will be key watchpoints

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In contrast with SMAD2/3/4 , only the blockade of the MAPK/ERK cascade by U0126 and the PI3K/AKT signaling by AZD5363 attenuated the effect of TGF- on c-MET phosphorylation as well as HGF gene expression (Fig