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Weight change and risk of venous thromboembolism: the Troms study

Regeneron Pharmaceuticals Sector: Muscle-preserving antibody combinations and GLP-1 therapy for obesity HQ: Tarrytown, NY Year Founded: 1988 Origin Story: Founded in 1988 by Leonard Schleifer, MD, PhD, a neurologist and assistant professor at Cornell University Medical College on the premise that drug discovery could be industrialized through proprietary antibody-generation technology

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(2013) using rodent models demonstrated that while chronic GIPR agonism alone could have neutral or even negative effects on body weight, co-activation of GIPR with GLP-1R resulted in a greater reduction in body mass and adiposity than GLP-1R agonism alone

Mechanotransduction for Muscle Protein Synthesis via Mechanically Activated Ion Channels