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In this study, we demonstrated the potential of modulating the host microenvironment to sensitize intracellular persisters to antibiotics and improve treatment outcomes

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Risk and Handling Precautions Risk Tier: MODERATE This rating reflects both peptides' bioactive activity at angiogenic and cytoskeletal signaling pathways in preclinical models, the absence of established human safety profiles for either compound, and the additional handling considerations specific to intranasal formulations

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