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Researchers are particularly interested in its behavior under metabolic stress, where mitochondrial-derived peptides appear to play a regulatory role in how cells adapt energy production to changing demands

A., Laatsch, C

The study also revealed an unexpected pathway-dependent response: in telomerase-positive cancer cell lines, telomere elongation occurred through alternative lengthening of telomeres (ALT) activation rather than telomerase upregulation, suggesting that the AEDG sequences interaction with telomere maintenance pathways is more complex than initially characterized

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