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Considering the potential for therapeutic development of (in)GSH, the established safety and tolerability data, biological plausibility, and pilot level clinical evidence of benefit are further supported with this demonstration that (in)GSH is able to augment brain GSH levels

Kindel TL, Wang AY, Wadhwa A et al (2025) Multi-society clinical practice guidance for the safe use of glucagon-like peptide-1 receptor agonists in the perioperative period

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It has a complicated pathogenesis associated with environmental modifications, genetic predispositions, deregulated dopamine metabolism, neuroinflammation, oxidative stress, and mitochondrial dysfunction (Gke okal et al., 2017