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Although most of the past research has focused on fibrillar A, soluble oligomeric A species are now considered to be of major pathological importance in AD

Acta 1853 , 24812491 (2015)

It is a contributor to many types of ailments and illnesses

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247 This decrease is directly related to abnormal chromosome segregation and increased micronucleus formation, suggesting that inactivation of centromere function is the core cause of mitotic defects in senescent cells