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We therefore hypothesized that a better understanding of the structure of CCR8 may provide new insights into its function and potentially facilitate the generation of future therapeutics aimed at this emerging target

Lipophilic drugs can cross the RBC lipid membrane by simple diffusion, while hydrophilic compounds can enter due to the aqueous channels or other membrane-facilitated or active transport systems such as Glut1 (Magnani et al., 2012)