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Description

Semaglutide slows stomach emptying and reduces appetite by mimicking glucagon-like peptide-1 (GLP-1), a hormone that regulates blood sugar and satiety

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This is achieved by alleviating the inhibition of carnitine palmitoyltransferase 1 (CPT1), which is mediated by the local production of malonyl-CoA at the outer membrane of the mitochondria, via ACC2

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Athletes should seek an official ruling

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Researchers continue to monitor this phenomenon in ongoing trials to ensure long-term cardiovascular safety, particularly for individuals with pre-existing heart conditions

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