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Detailed Category Analysis# Receptor Targets# Retatrutide : Triple agonist: GIP, GLP-1, and glucagon receptors simultaneously Tirzepatide : Dual agonist: GIP and GLP-1 receptors Advantage : Retatrutide Weight Loss Efficacy# Retatrutide : Up to 28.7% body weight reduction at 68 weeks (Phase 3 TRIUMPH-4)

Scar Placement : While the incision is typically placed low where underwear can hide it, patients with very large pannuses may need a higher scar to effectively remove all the excess tissue

Am J Physiol Regul Integr Comp Physiol (2014) 307(4):R46570

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26, 27 PSCs secrete various inflammatory cytokines/chemokines, 29, 30 which can participate in inflammatory processes and can also secrete collagen and have an essential role in fibrosis