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This is because the impact on health budgets could be so great that the system cannot sustain it

Notably, the deletion of lipogenic enzymes in the liver, such as acetyl-CoA carboxylase 1/2 (ACC1/2), has been reported to liberate NADPH for antioxidant processes, including GSH regeneration 87

Available from: [Accessed 4 Mar 2025]

Sufficient muscle mass means that even when youre sitting down, you could still be burning calories

When translated into the number of patients needing treatment, substituting semaglutide for other glucose-lowering agents would prevent one additional seizure for every 70 patients treated, and substituting semaglutide for SGLT2 inhibitors would prevent one additional seizure for every 131 patients treated