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Sericin exerts its protective effects by upregulating Nrf2 expression and enhancing endogenous antioxidant enzyme activity, thereby preserving cellular membrane integrity and preventing caspase-dependent apoptosis (90)

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The exemplary mimic, Dihexa, binds to HGF with extraordinary affinity (Figure 43), blocking HGF dimerization (Figure 44), and markedly augments the ability of HGF to signal to c-Met (Figure 45) and initiate cellular responses (as discussed above)

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Tyrosine is converted to cystine in p53 (Y220C) mutant proteins, resulting in an accessible crevice