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Limitations and Evidence Gaps The ipamorelin research base has substantial gaps: No completed phase 3 trials

or (2) The tumor is not more than 2 millimeters thick, with or without ulceration, or not more than 4 millimeters thick, without ulceration

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This includes individuals with HIV, autoimmune diseases taking steroids or other immunosuppressant drugs, those whove had organ or bone marrow transplants, or individuals undergoing chemotherapy

Some studies suggest modest improvements in joint pain and possibly cartilage markers in people with mild knee osteoarthritis