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Retatrutide is an investigational triple receptor agonist that targets the glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), and glucagon receptors simultaneously

Documented effects include endocrine disruption, neurotoxicity, reproductive toxicity, and propagation of antimicrobial resistance (AMR)

However, large-scale randomized controlled trials remain absent for both peptides

Pomegranate Sometimes added for an antioxidant/superfood angle, not central to weight-loss claims

Then, the sections were dehydrated with ethanol, mounted, and imaged with Leica fluorescence microscope (Leica DM6000B) using Leica LAS X software