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Brain 120 , 141157 (1997)

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This receptor is already meaningfully activated at the 2mg starting dose, which is why most researchers notice some appetite changes even during the first week

PT-141 given as an intranasal dose of 10mg 45-120 minutes before sexual interaction led to positive effects in 33.5% of the patients, compared with 8.5% of the patients in the placebo group [6]