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While severe low blood sugar is relatively rare when taking Mounjaro on its own, the risk increases significantly if a person combines it with other diabetes medications, like insulin or sulfonylureas

For type 2 diabetes, NICE recommends GLP-1 receptor agonists when triple oral therapy is ineffective and BMI is 35 kg/m or higher (with lower thresholds for certain ethnic groups)

Water molecules, enzymes, and potential microbial contaminants can begin to cleave the peptide bonds, slowly but surely rendering the compound useless

PMID: 116 HerckMAVWeylerJKwantenWJDirinckELWinterBYDFrancqueSMet al

There are situations where adjustments are necessary