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The Journal of the American Medical Association recently published diet and exercise guidance for people taking GLP-1s (3): Source: Mehrtash F, Dushay J, Manson JE
1996;313(Pt 3):697-710
American Academy of Neurology guidelines on treating painful DPN recommend that clinicians evaluate oral, topical and nonpharmacologic therapies for patients with painful diabetic polyneuropathy, and emphasizes switching between drug classes rather than trying multiple agents within the same class if one fails [63]
Moreover, quantitative analysis of wound width over time revealed a linear relationship for all treatment conditions (y DMEM = 2.997x+88.2
Practical mitigations: Warm the vial about 10 minutes before drawing Inject slowly (a 5-second push) 5 mL reconstitution (the standard for larger vials) halves the concentration and reduces concentration-dependent burn the trade-off is injecting 0.2 mL / 20 units instead of 0.1 mL / 10 units per dose Inject deeper subQ rather than intradermal the upper dermis has more mast cells and reacts more visibly Dont co-inject with NAD+
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