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Caffeine is the worlds most widely used psychoactive substance, and over-consumption can cause diarrhea, twitching, racing heartbeat, and nervousness otherwise known as the caffeine jitters. Some say the caffeine content is dangerous, but its really just a bit more than a small cup of coffee

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References Gahl WA, Thoene JG, Schneider JA (2002) Cystinosis

J Appl Ecol 25:20112018 Wang F, Chen Z-H, Liu X, Colmer TD, Shabala L, Salih A, Zhou M, Shabala S (2017) Revealing the roles of GORK channels and NADPH oxidase in acclimation to hypoxia in Arabidopsis