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Toxic lipid peroxides can be converted into nontoxic lipid alcohols (L-OH) in the presence of GPX4 and GSH to inhibit ferroptosis [21]

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At present, relevant studies have confirmed that the expression of ALOX12 can reasonably predict the prognosis of patients, and ALOX12 can be used as a predictor of tumor prognosis [36,37,38]

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