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While this has not been observed in humans, it remains a theoretical risk, and patients with a history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) are typically advised against using Semaglutide

Clinical appropriateness depends on the individual, their health background, and professional medical assessment

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The company has also invested more than $18 billion to update its existing US manufacturing facilities, including a $1.2 billion investment at its Indianapolis site and an injectable manufacturing facility in Wisconsin, recently acquired from Nexus Pharmaceuticals.

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