This is roughly the same amount of weight that patients on Mounjaro lose over the course of treatment
Far along in research and development is Eli Lillys retatrutide, a triple agonist that adds glucagon to GLP-1 and GIP, and the requisite studies are underway.1,14 In addition, theres cagrisema from NovoNordisk, a blend of semaglutide (GLP-1 agonist) and a long-acting amylin (another pancreatic hormone) analog cargrilintide
It links degradation to reduced appetite suppression, diminished weight loss outcomes, and inconsistent glucose control
A separate 2024 study of 290 adults with obesity given oral semaglutide for three months found that free T3 decreased, free T4 rose slightly, and TSH fell during treatment
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