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Under physiological conditions, GSH quenches oxidizing substances (such as reactive hydroxyl free radicals, peroxynitrite, and H 2 O 2 ) directly or reduces hydrogen peroxide (or lipid peroxide (lipid-OOH)) to water (or the corresponding lipid alcohol (lipid-OH)) under the catalysis of GPX (summarized in Fig

In pursuit of the unknown, our research group performed a variety of clinical tests on GSH level quantitation in specific brain regions (the hippocampus, frontal cortices and cingulate cortices) using non-invasive MRS techniques to evaluate GSHs role as an early diagnostic biomarker for AD

Unless otherwise specified, variables are presented as the mean (standard deviation)

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13: DeFoor MT, Dekker TJ