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The most common side effects at higher doses (8 mg and 12 mg weekly) are gastrointestinal, including nausea, vomiting, diarrhoea, and constipation

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The availability of animal models for experimental liver cirrhosis (carbon tetrachloride, thioacetamide, bile duct ligation, D-galactosamine) helped us to better elucidate the role of IGF-I in this pathology

At the same time, you know, we used the procedure itself, you know, whatever procedure we're doing is stressful for the patient and that can cause them to, I would say, release a lot of glycogen into glucose in their bloodstream

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