Other mechanisms of glucagon reduction include increased production of somatostatin, a potent glucagon inhibitor, in the delta cells of the pancreas which can exert a paracrine effect on alpha cells
Moreira GV, Azevedo FF, Ribeiro LM, Santos A, Guadagnini D, Gama P, et al
What is fascinating is that their effects are not limited to alcohol: preclinical and correlational data indicate possible benefits in decreasing use of nicotine and opioids, which makes sense as alcohol, cannabis, opioid, and nicotine use disorders cluster together genetically into one brain disorder
Most patients can self-administer the injections at home after receiving proper training from their healthcare provider
So I know there were many different ways you could have protected or extended the half-life one way or another, but this seemed to be a breakthrough of many along the chain of breakthroughs