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As weight loss medications continue to evolve, researchers are also studying what comes next beyond semaglutide and tirzepatide
Meta-analyses suggest that a 710% weight reduction resulting from caloric restriction can significantly improve liver steatosis, as indicated by liver enzyme activity, histological assessment of steatosis and inflammation, albeit with less certainty regarding its impact on fibrosis (87)
Because its considered off-label, theres little clinical evidence to show whether this kind of do-it-yourself dosing is actually effective, or just anecdotal