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159 Importantly, clinicians should understandand emphasize to individuals taking GLP-1sthat increased protein intake alone is likely inadequate to support the preservation of muscle mass in the absence of structured resistance/strength training

If supplementation is advised, oral cyanocobalamin at doses of 50150 micrograms daily is typically used for diet-related deficiency prevention, while intramuscular hydroxocobalamin is the standard treatment in the UK for pernicious anaemia or malabsorption conditions

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By providing the body with active methylcobalamin, you force the remethylation pathway to regain its normal, healthy activity