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Randomized phase II study of erlotinib in combination with placebo or R1507, a monoclonal antibody to insulin-like growth factor-1 receptor, for advanced-stage non-small-cell lung cancer

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On the other hand, inability to eat even small meals, severe nausea lasting more than a few days after dose escalation, and significant dizziness or lightheadedness suggest the dose is too high

They also have been described as white in color and sometimes caseous in nature, as well as round and small, pin-point-sized, or large sheets covering a wider part of the mouth (Wyatt et al., 1972