We assessed whether serum insulin-like growth factor 1 (IGF-1) levels, a surrogate for GH levels, correlate with sexual function scores in 65 men who completed the Sexual Health Inventory for Men (SHIM) and Expanded Prostate Cancer Index Composite (EPIC) questionnaires, and had serum IGF-1 and testosterone levels determined
Across all patients, baseline NS5A polymorphisms A30K/M/R/S/T/V and Y93H were the most frequent, detected in 12 (9.3%, 2 with A30K) and 8 (6%) patients, respectively (Supporting Table S4)
Cross-species dose conversion requires extensive pharmacokinetic and pharmacodynamic studies beyond simple body weight or surface area calculations
Back Zander, M, Madsbad, S, Madsen, JL, Holst, JJ (9 March 2002) 'Effect of 6-week course of glucagon-like peptide 1 on glycaemic control, insulin sensitivity, and beta-cell function in type 2 diabetes: a parallel-group study', The Lancet , 359/9309, 824-30
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