OA synovitis directly contributes to several clinical signs and symptoms, including joint swelling and effusion, and reflects the structural progression of the disease 8,9
Thankfully, compounded semaglutide offers a more affordable alternative with the same active ingredient, typically priced between $300 and $600 per month or less
As a weight loss drug, semaglutide is intended to be used along with lifestyle changes like a reduced-calorie diet and regular physical activity
Both, semaglutide and liraglutide, by binding to GLP-1R, can activate cAMP and PKA signaling cascades
However, when she attempted to move up to 1.0 mg, the side effects - bloating, gas, and fatigue - became overwhelming