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Efficient generation of multi-copy strains for optimizing secretory expression of porcine insulin precursor in yeast Pichia pastoris

Saxenda is approved for weight management in adults and adolescents with obesity (BMI 30) or overweight (BMI 27) with conditions like high cholesterol, high blood pressure, or type 2 diabetes

Preclinical studies using COPD mouse models revealed that GLP-1RA therapy significantly improved lung function and reduced both morbidity and mortality

Adults over 30 with declining growth hormone, athletes seeking recovery optimization, and individuals pursuing body recomposition are typical candidates

This study was supported by the National Natural Science Foundation of China (no