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In the only direct evaluation of brain insulin resistance in PD, insulin signaling abnormalities were identified in the dorsolateral prefrontal and posterior parietal cortex of those with cognitive impairment, but not in those who were cognitively normal [72]

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Patients with type 2 diabetes or obesity may have additional risk factors for infections or other conditions that cause lymphadenopathy, making it essential to evaluate swollen lymph nodes thoroughly rather than automatically attributing them to GLP-1 therapy

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