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Fiocco U, Rosada M, Cozzi L, et al

However, numerous non-motor symptoms may accompany the hallmark motor symptoms, which include loss of smell, pain syndromes, depression, anxiety, urinary and gastrointestinal dysfunction, sleep disorders, cognitive impairment, apathy, and weight loss [15, 16]

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In DOPA-stained epidermis from most patients with neurofibromatosis, the density of melanocytes is higher in both CALMs and normal adjacent skin, in comparison with healthy individuals