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Additionally, BEST4+ enterocytes, a recently identified novel subtype of absorptive cells predominantly enriched in mature enterocytes 16 and unique to the human intestinal epithelium 21 , showed increased estimated proportions in EV39-treated premature intestinal organoids (Fig

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Not needing human BE trials provides a great benefit in that it reduces drug development costs and eliminates unnecessary clinical trials (12)

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post-receipt handling is set by the end laboratory