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Similar content being viewed by others Introduction Reactive oxygen species (ROS) are byproducts of the normal metabolic function of any cell in the body and damage proteins, lipids and nucleotides, thereby interfering with a myriad of important cellular processes 1

It is generally observed after protracted exposure but also after acute treatment (acute tolerance) and it is not observed for all the pharmacological effects

Before receiving folic acid or methylcobalamin, patients should be assessed for deficiency and appropriate therapy started concurrently

10.1016/s0896-6273(03)00714-1 45 GoldbergJ

This is not a technical footnote