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In some respects, we are entering the fourth generation of nAbs: the first was serum antibodies, the second purified polyclonal antibodies, the third monoclonal antibodies, and now, super-antibodies

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The peptide accelerates early collagen organization and stimulates expression of the EGR-1 gene along with its repressor NAB2, creating a regulatory feedback loop that prevents excessive fibrosis while promoting organized tissue remodeling

doi: 10.3389/fimmu.2023.1215612 28 SaenkoVSFeofilovIVFrolovaEATsarichenkoDGSysinSASalpagarovaAIet al